Top 10 Best Systemic Enzymes [2022]

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Are you looking for the Best Systemic Enzymes. You are in the right place. Our team went through about 45092 reviews available online for Systemic Enzymes. We chose the finest ones, and prepared this list for you.

Comparison Chart of Top 10 Systemic Enzymes

NoProductScoreAction
1Pro-OneZyme Best Proteolytic Systemic Enzymes Supplement with Nattokinase & Seapose - 90 Capsules9.6Buy On Amazon
2Serrapeptase Enzymes by MaryRuth's - Vegan Serrapeptase High Potency Sinus Pills for Allergy Support9.6Buy On Amazon
3Excellacor – Proteolytic Systemic Enzymes Formula – with Enteric-Coated Serrapeptase - Total Body Support - 90 Vegetarian Capsules - AST Enzymes9.6Buy On Amazon
4HCP Formulas - Fibrenza - Systemic Enzyme Complex with Fibrinolytic & Proteolytic Enzymes - Fibrin Defense9.6Buy On Amazon
5Garden of Life Joint Support Supplement9.2Buy On Amazon
6Vitälzym Proteolytic Systemic Enzymes Liquid Gel Capsules with Serrapeptase9.2Buy On Amazon
7Excellacor-450 Vegetarian Capsules-Premium Natural Systemic Enzyme Formula-Total Body Support - Contains Enteric-Coated Serrapeptase - Supports healthy Inflammation & Joints8.6Buy On Amazon
8Pure Encapsulations Systemic Enzyme Complex - Supplement to Support Muscle8.4Buy On Amazon
9Vitälzym Original Proteolytic Systemic Digestive Enzyme Formula Serrapeptase Source - Anti-Inflammatory Immune and Joint Support Increase Blood Flow Cardio Function - Healthy Men Women (90 Capsules)8.4Buy On Amazon
10Serracor-NK –Proteolytic Systemic Enzyme Formula – Contains Enteric-Coated Serrapeptase and Enteric-Coated Nattokinase - Circulatory and Respiratory Support – 90 Vegetarian Capsules–AST Enzymes8.4Buy On Amazon

Systemic Enzymes Reviews

We have checked about 45092 reviews for systemic enzymes. It was quite difficult to shortlist the ideal ones from thousands of variants online. However, we've tried our best to make sure that you get only the best one from our suggestions.

Disclaimer: As An Amazon Associate We Earn From Qualifying Purchases.

Table Of Content:

1. Pro-OneZyme Best Proteolytic Systemic Enzymes Supplement with Nattokinase & Seapose – 90 Capsules

  • UNIQUELY FORMULATED – ProOneZyme is the only supplement that contains 6 of the best quality proteolytic enzymes in one convenient vegan capsule.
  • ALL NATURALLY MADE – Contains no wheat, yeast, soy or gluten.
  • PERFORMANCE DRIVEN – Proteolytic Systemic Enzymes gives active enzymes the body can use.
  • POWERFUL AND PROVEN – Nattokinase and Seaprose is gentle on the stomach.
  • 100% RISK FREE GUARANTEE! If for any reason you are not satisfied with ProOneZyme simply return any unused portion for a full no hassle, 30-Day Money-Back Guarantee! Third Party Tested and manufactured in a GMP Facility.

2. Serrapeptase Enzymes by MaryRuth’s - Vegan Serrapeptase High Potency Sinus Pills for Allergy Support

  • Serrapeptase Systemic Enzymes: This proprietary blend of enteric-coated Serrapeptase (also known as Serratiopeptidase) and a Protease blend is combined with enzyme enhancing vitamins and minerals to support your overall health.
  • Multiple Benefits: Serrapeptase may help to support the body’s circulatory system, healthy tissue homeostasis, and the body’s natural inflammation process.
  • Advanced Enzyme Complex: 120,000 SPU Serrapeptase in each capsule.
  • Easy Efficient Absorption: Formulated to be taken systemically, not digestively.
  • Free of Most Common Allergens: MaryRuth’s Serrapeptase Systemic Enzymes are Non-GMO & Vegan.

3. Excellacor – Proteolytic Systemic Enzymes Formula – with Enteric-Coated Serrapeptase – Total Body Support – 90 Vegetarian Capsules – AST Enzymes

  • ADVANCED SYSTEMIC ENZYME FORMULA: Exclzyme is a potent blend of serrapeptase, proteases and herbs that support the body’s natural response to inflammation and healthy joint function.
  • RANGE OF USE: Supports the body’s natural response to inflammation including fatigued muscles and joint function, healthy blood circulation, and healthy fibrin metabolism.
  • ACHIEVE OPTIMUM HEALTH: Elimination of potentially waste substances from the body is a crucial part in the metabolic processes for optimal health.
  • QUALITY ASSURED: All products by AST Enzymes are manufactured in the USA.

4. HCP Formulas – Fibrenza – Systemic Enzyme Complex with Fibrinolytic & Proteolytic Enzymes – Fibrin Defense

  • FIBRENZA SUPPLEMENT: An advanced blend of 13 powerful systemic enzymes! HCP Formulas’ Fibrenza is a natural systemic enzyme complex.
  • INFLAMMATION & CARDIOVASCULAR SUPPORT: Aging lowers your body’s ability to produce sufficient levels of enzymes, often leading to inflammation and build-up of fibrin.
  • ANTIOXIDANT: Not only are systemic enzymes powerful anti-inflammatory and anti-fibrin agents, but they also possess profound antioxidant properties.
  • SUPERIOR DELIVERY: Fibrenza utilizes a technologically advanced capsule without phthalates or chemicals.
  • PREMIUM INGREDIENTS: HCP Formulas specializes in ultra-premium nutraceutical supplements to better support your health.

5. Garden of Life Joint Support Supplement

  • JOINT SUPPORT: Wobenzym N contains plant-based enzymes, pancreatic enzymes and plant antioxidants to help maintain healthy joints, mobility and flexibility.
  • SYSTEMIC ENZYMES: This clinically studied formula works holistically through the entire body to support overall joint health.
  • JOINT PAIN SUPPLEMENTS: This supplement provides temporary relief from aches, pains and muscle soreness due to everyday activity.
  • SYNERGESTIC: This enzyme blend helps maintain healthy joints, mobility and flexibility
  • ENTERIC COATED: These powerful yet delicate enzymes are protected by an enteric coating for optimal absorption and utilization in the bloodstream.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers’ recommendations, when provided.

6. Vitälzym Proteolytic Systemic Enzymes Liquid Gel Capsules with Serrapeptase

  • Enteric Coated Advanced Delivery Method: Vitalzym high potency gel caps are unlike any tablet or powder based enzyme product available on the market today.
  • Ingredients: Vitalzym Extra Strength premium softgels are the original, all-natural, vegetarian multi enzyme complex.
  • Protect Your Health: Living well in modern times can be stressful and a source of pain at times.
  • Small, Easy To Swallow Gel Caps: Our advanced encapsulations deliver reliable results that offer pure, potent enzymes with reliable consistency and unrivaled absorption rates.
  • Made In Japan: Created by a team of international scientists, Vitalzym works best when combined with exercise, proper fluid intake, and a healthy diet.

7. Excellacor-450 Vegetarian Capsules-Premium Natural Systemic Enzyme Formula-Total Body Support – Contains Enteric-Coated Serrapeptase – Supports healthy Inflammation & Joints

  • Vegetarian Systemic Enzyme Formula
  • Total body inflammation support
  • Supports overall metabolic health
  • Healthy blood circulation & cleansing
  • Recovery from muscle soreness

8. Pure Encapsulations Systemic Enzyme Complex - Supplement to Support Muscle

  • Muscular Health: Systemic Enzyme Complex is formulated to support the overall health of the musculoskeletal system.
  • Muscle Comfort: Supports a healthy response to temporary muscle soreness and temporary joint discomfort associated with exercise.
  • Joint & Cartilage Health: Supports healthy connective tissue, as well as joint and cartilage health.
  • Pure Quality: Our supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts, then carefully manufactured and tested to verify their potency and purity.
  • Pure Difference: What makes us different isn’t just our process or what goes into our supplements — what we leave out matters, too.

9. Vitälzym Original Proteolytic Systemic Digestive Enzyme Formula Serrapeptase Source - Anti-Inflammatory Immune and Joint Support Increase Blood Flow Cardio Function - Healthy Men Women (90 Capsules)

  • American Made, Essential for Health, Plant Based: Not All Complete Digestive System Enzyme Products Are Made The Same – Pay For True Quality & You Will Not Be Disappointed.
  • The Best Vegetarian Digestion Supplement & Remedy: Our Premium Strength Super Gut Defense Formula contains everything you need for full-body support: Protease, Serrapeptase, Papain, Bromelain, Amylase, Lipase, Rutin, & Amla.
  • Advanced, Broad Spectrum Caps Promote Wellness: Our complex extract provides the optimal potency level of proteolytic enzymes that may assist with IBS, gas, inflammation, regulating your immune system, removing excess plaque & fibrin (fibrous tissue), & support the return of blood volume & flow.
  • Fast Response, Organic, Calms Indigestion & Assists With IBS, Gas, Bloating: Regain bowel comfort with our perfect synergistic blend of systemic and digestive enzymes.
  • Formulated for Active Vitality Enhancement Plus Recovery: High-quality pure powder filled capsules that break down in your stomach provide digestive support with every dose.

10. Serracor-NK –Proteolytic Systemic Enzyme Formula – Contains Enteric-Coated Serrapeptase and Enteric-Coated Nattokinase – Circulatory and Respiratory Support – 90 Vegetarian Capsules–AST Enzymes

  • ADVANCED SYSTEMIC ENZYME FORMULA: Serracor-NK is a powerful blend of enteric-coated serrapeptase and enteric-coated nattokinase, systemic enzymes studied for their fibrinolytic properties, with antioxidant herbs, CoEnzyme Q10 and magnesium.
  • RANGE OF USE: Supports the body’s natural response to inflammation including respiratory and sinus, and cardiovascular health.
  • ACHIEVE OPTIMUM HEALTH: Excess fibrin in the body can do more harm than good.
  • QUALITY ASSURED: All products by AST Enzymes are manufactured in the USA from FDA registered facility that follows GMP guidelines.

Systemic Enzymes Buying Guide


Does the thought of finding a great Systemic Enzymes stress you out? Has your mind been juggling between choices when it comes to buying Systemic Enzymes in general, specifically regarding which model to choose?
If that’s the case, know that you’re not alone. Many people find it tough to buy the perfect Systemic Enzymes for themselves. We understand the stress associated with the buying process!
Since you’re here, you are obviously curious about Systemic Enzymes Reviews. You’ve been bombarded with information, so you need to find a reputable source with credible options before you make any decisions on which product would be best for your needs.
There are many sources that’ll provide you with that information- buying guides or ratings websites, word-of-mouth testimonials from friends or family members, online forums where users share their personal experiences, product reviews specifically found all over the internet and YouTube channels. Only thorough research will ensure that you get the right product.
But that’s not always easy, right? That's why we've taken time to compile a list of the best Systemic Enzymes in today's market, on your behalf, so that there will be no more worries for you.
How did we come up with the list, you ask? How did we create this buying guide?
  • First, our algorithms collected as much information available about these products from trusted sources.
  • We employed both Artificial Intelligence and large data volume to validate all collected information.
  • Then our AI ranked them on their quality-to-price ratio using industry-standard criteria that let us pick the best Systemic Enzymes currently on the market!
The products aren’t chosen randomly. We consider several criteria before assembling a list. Some of the criteria are discussed below-
  1. Brand Value: What happens when you go for a not-so-reputable brand just because the price seems cheap? Well, the chance of getting a short-lasting product goes higher. That’s because the renowned brands have a reputation to maintain, others don’t.
Top Systemic Enzymes brands try to offer some unique features that make them stand out in the crowd. Thus hopefully, you’ll find one ideal product or another in our list.
  1. Features: You don’t need heaps of features, but useful ones. We look at the features that matter and choose the top Systemic Enzymes based on that.
  2. Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products of higher specifications, but with the right balance.
  3. Customer Ratings: The hundreds of customers using the Systemic Enzymes before you won’t say wrong, would they? Better ratings mean better service experienced by a good number of people.
  4. Customer Reviews: Like ratings, customer reviews give you actual and trustworthy information, coming from real-world consumers about the Systemic Enzymes they used.
  5. Seller Rank: Now, this is interesting! You don’t just need a good Systemic Enzymes, you need a product that is trendy and growing in sales. It serves two objectives. Firstly, the growing number of users indicates the product is good. Secondly, the manufacturers will hopefully provide better quality and after-sales service because of that growing number.
  6. Value For The Money: They say you get what you pay for. Cheap isn’t always good. But that doesn’t mean splashing tons of money on a flashy but underserving product is good either. We try to measure how much value for the money you can get from your Systemic Enzymes before putting them on the list.
  7. Durability: Durability and reliability go hand to hand. A robust and durable Systemic Enzymes will serve you for months and years to come.
  8. Availability: Products come and go, new products take the place of the old ones. Probably some new features were added, some necessary modifications were done. What’s the point of using a supposedly good Systemic Enzymes if that’s no longer continued by the manufacturer? We try to feature products that are up-to-date and sold by at least one reliable seller, if not several.
  9. Negative Ratings: Yes, we take that into consideration too! When we pick the top rated Systemic Enzymes on the market, the products that got mostly negative ratings get filtered and discarded.

These are the criteria we have chosen our Systemic Enzymes on. Does our process stop there? Heck, no! The most important thing that you should know about us is, we're always updating our website to provide timely and relevant information.
Since reader satisfaction is our utmost priority, we have a final layer of filtration. And that is you, the reader! If you find any Systemic Enzymes featured here Incorrect, irrelevant, not up to the mark, or simply outdated, please let us know. Your feedback is always welcome and we’ll try to promptly correct our list as per your reasonable suggestion.